Genome Centre

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About Us

Loading the Tecan Robot
Running A MiSeq
Preparing an Illumina Array

Bart's and the London Genome Centre is the genomics core facility at Queen Mary, University of London, supporting researchers since 2000. We work with academic (both with and without QMUL affiliation) and corporate partners, on a not for profit basis, to achieve their genomics research aims. Ours is a highly collaborative model, providing a custom service, offering advice on design and interpretation as required. We are always interested in trying novel approaches to genomic challenges.

Our services are supported by some of the key genomics platforms - Next Generation Sequencing, Arrays and Robotics - but we are particularly active in four key areas;

Single Cell genomics. We run the Fluidigm C1 to capture single cells followed by whole transcriptome profiling or targeted DNA sequencing.

RNA sequencing has replaced arrays as the method of choice to profile the transcriptome. We have optimised processes for mRNA, total RNA and miRNA sample prep and analysis.

DNA methylation profiling We support Whole Genome Bisulphite Sequencing (WGBSS), Reduced Representation Bisulphite Sequencing (RRBS)or using the powerful Illumina Methylation EPIC arrays for human samples for genome wide profiles. This can be extended by targeted Bisulphite Sequencing, using Fluidigm Access Arrays

Targeted DNA sequencing in panels of genes using approaches including Fluidigm Access Arrays and Agilent SureSelect chemistries.

These and our other services are listed in more detail on our services page, or discuss with the centre manager
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