Intercalated BSc in Experimental Pathology
Outlines of Current Projects

Below are listed the titles of a number of the experimental pathology projects on offer. Click on the titles to see a brief (or not so brief) outline. These should not be regarded as precise descriptions of the work involved, but are intended to give you enough information to decide if they might be of interest. You are encouraged to discuss all the projects that interest you with the relevant supervisors (click on there names for contact details) and feel free to do this at any time between now and the start of the course. In the interests of efficiency please try and arrange these meetings so that several of you see a given supervisor at the same time, although I realise that this may be difficult at times. During the first week of the course, supervisiors and students will have an opportunity to meet and a final decision about who does which project will be made by the end of that week. For details about project structure click here and for details about the course as a whole, click here. Finally, please contact Steve Greenwald or Cathy Baker at any time if you want more information or any other advice.

August 2009.

Supervisor Project name
Dr Narendra Aladangady Retinopathy of Prematurity in Relation to Hyperglycaemia
Prof Malcolm Alison and Dr Wey-Ran Lin Identifying clonal populations in human tissues using mtDNA mutation and gene methylation
Dr Dan Berney Tissue microarray and immunochemistry analysis prostate, penile or renal cancer
Dr Kristin Braun Investigating the role of c-Myc in thymic epithelial carcinomas
Professor Rino Cerio Expression of cKIT mutation in cutaneous melanoma and potential in target treatment of metastases
Dr Frank Hills The effects of heprin on growth factor-mediated trophoblast function in pre-eclampsia
Dr Salvador Diaz-Cano

Topographic analysis of ubiquitin and P38-MAPK in differentiated follicular cell thyroid neoplasms

Prof Steve Greenwald A pilot study to investigate the effects of vitamin D2 or D3 supplementation on metabolic parameters in people at risk of type 2 diabetes
Prof Steve Greenwald and Dr R Pearse Assessing the feasibility of a new method for the noninvasive measurement of endothelial function in conduit arteries.
Prof Steve Greenwald Vascular stiffness in elite athletes

Prof Inderjeet Dokal and Dr Tom Vulliamy

The pathophysiology and genetic basis of dyskeratosis congenita
Prof Jo Martin Novel spinal cord protein
Prof Jo Martin Dynein cell biology
Prof Jo Martin Phagocytosis
Prof Jo Martin Gastrointestinal disease
Dr Graham Neill Defining mechanisms of hormone-sensitivity in epithelial cancer
Prof Edel O'Toole The role of type VII collagen in apoptosis in skin.

Dr Mike Sheaff and Prof Yacoob

A review of kidney biopsies from diabetic patients and a search for a potential role for amylin in diabetic glomerulopathy
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