Leading Cancer researchers
The results of the 2008 Research Assessment Exercise (RAE) placed Barts and The London School of Medicine in the top 5 medical and dental schools in England for quality of research.
Professor Nicholas Lemoine
Professor Nicholas Lemoine is the Director of both Barts Cancer Institute and the Cancer Research UK Clinical Centre. He also leads the Centre for Molecular Oncology & Imaging, where the research of four groups focuses on the molecular pathology of solid malignancies, gene transcription biology, cell survival signalling, and molecular therapeutics including gene therapy and vaccine approaches.
Profile: Professor Nicholas Lemoine
Professor Jack Cuzick
Professor Jack Cuzick leads research into the screening and prevention of cancer. Key areas of interest are cancers of the breast, uterine cervix, prostate and colon. In these areas there are activities encompassing prevention studies, screening studies, treatment comparisons, prognostic factors for survival, and aetiological studies of risk factors for developing malignant disease.
Profile: Professor Jack Cuzick
Professor Frances Balkwill
Professor Frances Balkwill’s work has led to the realisation that cancers possess a complex cytokine network, that a pro-inflammatory tumour micro-environment is involved in tumour promotion and spread, and that there are strong links between the processes of chronic inflammation and cancer.
Profile: Professor Frances Balkwill
Professor Bart Vanhaesebroeck
Centre Lead, Cell Signalling Professor Bart Vanhaesebroeck joined the Barts Cancer Institute at Barts and The London School of Medicine and Dentistry from the Ludwig Institute for Cancer Research (University College London), to set up the Centre for Cell Signalling in June 2007.
His research group’s key interest lies in understanding signalling through PI 3- kinases (PI3Ks), combining fundamental research with efforts to translate findings into diagnostic and therapeutic applications.
Profile: Professor Bart Vanhaesebroeck
Professor John Gribben
Professor John Gribben leads the newly established Centre for Experimental Cancer Medicine. The main objective of the Centre is to provide a centre of excellence to facilitate translational cancer research from basic scientific discovery to the delivery of novel approaches to care of patients with cancer.
Profile: Professor John Gribben
Dr Claude Chelala
Dr Claude Chelala’s research focuses on the development and application of computational solutions to cancer research including the design and implementation of a generic model for the organisation, integration and mining of complex data for cancer research.
Dr Thorsten Hagemann
Dr Thorsten Hagemann’s major research focus is to understand the fundamental mechanisms by which TNFα signalling promotes cancer; with particular reference to the role of macrophages and their phenotype in carcinogenesis.
Professor Iain McNeish
Professor McNeish joined Barts Cancer Institute in May 2004. He trained in medicine at Oxford and did his PhD at the Institute of Cancer Studies at the University of Birmingham. From 1998 to 2004, he combined training in medical oncology at Hammersmith and Charing Cross Hospitals with post-doctoral research at the Molecular Oncology Unit at Imperial College.
The focus of his research is ovarian cancer, also his clinical sub-specialisation. His research programme focuses on abnormalities in apoptosis and cell cycle control in ovarian cancer as a target for gene and viral therapy.
Profile: Professor Iain McNeish

